Pharmaceutics and pharmaceutical technology
Preformative studies, design and development of innovative formulae to be used in medical, biomedical, cosmetic and nutraceutic environment and the related toxic/pharmaceutical features.
Main research lines:
- interactions of drugs/biomembranes and drugs/proteins,
- biodegradable micro-particules for the prolonged release of conventional and biotechnological drugs,
- nanotechnologies for transport and direction of bioactive molecules at cellular and/or tissue level,
- innovative formulations for pulmonary transportation of drugs,
- engineered polymeric platforms for mucose transport of bioactive molecules,
- Hydrogels for the release of bioactive molecules and scaffold for tissue regeneration,
- studies about reological and transport properties of biomaterials,
- identification and dosage of xenobs within compex matrix,
- synthesis and characterization of prodrugs, provitamins and enzym-activated cosmoceutics,
- innovative cosmetic formulation and related studies for transdermic permeatio.
Research groups
- Pharm-Analysis & Bio-Pharm
Biochromatography; drug-biomembranes and drug-protein interaction studies; kinetic studies; development and quality assurance of drug formulations.
Research Team:
BARBATO Francesco (PO)
GRUMETTO Lucia (RU)
Website: www.drugdelivery.unina.it
- BioNanoMed
Delivery and targeting of drugs and bioactive compounds by using innovative formulations based on lipidic nanosystems (liposomes, ethosomes, transferosomes), polymers, hydrogels and polymeric films.
research Team:
DE ROSA Giuseppe (PA)
BIONDI Marco (RU)
MAYOL Laura (RU)
Website: www.drugdelivery.unina.it
- DelTech
Design of controlled-release formulations using biodegradable micro-, nano-carriers for the delivery of small molecules, proteins, oligonucleotides and DNA. Design of tumor-homing nanoparticles.
Research Team:
QUAGLIA Fabiana (PA)
MIRO Agnese (PA)
UNGARO Francesca (PA)
- Cosmeceutica
Synthesis and characterization of prodrugs, provitamins and topic drugs. Studies of transdermal drug delivery in vitro with Franz's cells. Innovative formulations for cosmetics and drugs application on the skin with biocompatible materials.
Research Team:
SACCHI Antonia (PA)
LANERI Sonia (RU)
- PRODRUGS
The research activity is focused on design and synthesis of new NSAID's prodrugs in order to decrease the gastro-intestinal toxicity , while maintaining the pharmacological activity . Moreover, when possible, in order to reduce pollutants and improve the yields, the synthesis of these pro drugs is carried out according to the principles of green chemistry.
Research Team:
MARIA GRAZIA Rimoli (PA)