The Call for Admission to the PhD Degree in Pharmaceutical Sciences is issued every year between April and June.

Undergraduates can also apply as long as they achieve the qualification by the date of enrollment in the course.

Possible reference for further information: Dr. Rosa De Vivo tel. 081-678745

Admission procedure

Evaluation of qualifications: admission of candidates is based on the evaluation of their Curriculum studiorum and on the qualifications presented at the time of application. In compiling their CVs, candidates must include the following information:

  • date of graduation and grade of the master's degree
  • detailed list of exams taken and relative marks
  • any scholarships or research grants obtained (and similar qualifications)
  • certificates of participation in post-graduate university courses
  • certificates of participation in previous research groups
  • certificates of participation in internships
  • prizes or other qualifications that can be evaluated (eg second degrees, etc.)

The request for admission may possibly be supplemented by a summary of the degree thesis, the list of any scientific publications and a possible reference letter from a university professor.

Linguistic knowledge: Candidates must also demonstrate good knowledge of a foreign language. Knowledge of the foreign language will be assessed by reading and translating a text (identified during the test itself) into the foreign language chosen by the candidate among those determined by the announcement, and a brief conversation on the content of what has been read.

Oral exam: the oral exam is aimed at ensuring a suitable comparative evaluation of the candidates and at ascertaining the preparation and aptitude of the candidate for scientific research. The qualifications and topics covered by the oral exam must be relevant to the relevant scientific-disciplinary sectors of the PhD course; the interview will focus on a specific topic chosen by the candidate from the list that will be available in this page after the opening of the call.

Doctoral Course in Pharmaceutical Sciences –XXXIX Cycle-List of topics for the oral admission



Tutor e co-tutor, special fundings

Topic 1

Bioactive non-viral nanovectors for RNA delivery

Prof. De Rosa Giuseppe

CN3-Spoke 3 (Neurodegeneration)

Topic 2

Design and synthesis of antisense oligonucleotides (ASOs) modified with small molecules

Prof.ssa Sepe Valentina 

CN3-Spoke 4 (Metabolic and Cardiovascular disease)

Topic 3

Design of Modulators of miRNAs Involved in Cardiovascular and Metabolic Disorders through Machine/Deep Learning Techniques and Biosimulations

Prof. Lavecchia Antonio 

CN3-Spoke 4 (Metabolic and Cardiovascular disease)

Topic 4

Inhalable RNA-loaded nanoplatforms for local management of lung fibrosis and chronic inflammation

Proff. Ungaro Francesca-Costabile Gabriella 

CN3-Spoke 5 (Inflammatory and Infection disease)

Topic 5

Pharmacokinetic and pharmacodynamic evaluations of RNA-loaded nano-delivery systems for the treatment of pulmonary inflammation

Prof.ssa D'Emmanuele di Villa Bianca Roberta


CN3-Spoke 5 (Inflammatory and Infection disease)

Topic 6

Design, synthesis, structural characterization, and evaluation of the biological properties of therapeutic oligonucleotides based on DNA, RNA and analogs

Prof. Galeone Aldo


CN3-Spoke 6 (RNA Drug development)

Topic 7

Physicochemical investigations on RNA drug based and energetics of their interaction with biomolecular targets

Prof.ssa Giancola Concetta


CN3-Spoke 6 (RNA Drug development)

Topic 8

Application of computational methods to investigate and optimize the structural stability and the pharmacokinetic properties of lipid-based RNA nanocarriers

Prof.ssa Moraca Federica


CN3-Spoke 7 (Biocomputing)

Topic 9

Development of chicken ChorioAllantoicMembrane (CAM)-based cancer models to screen trafficking, delivery efficiency, and toxicity of RNA based nanoplatforms

Prof.ssa Russo Annapina


CN3-Spoke 8 (Platform for DNA-RNA delivery)

Topic 10

Peptide-based nanostructures as delivery tools for active pharmaceutical ingredients

Proff. Diaferia Carlo-Accardo Antonella


CN3-Spoke 8 (Platform for DNA-RNA delivery)

Topic 11

Polymeric nanoplatforms for precision targeting of siRNA to solid tumors

Prof.ssa Conte Claudia

CN3-Spoke 8 (Platform for DNA-RNA delivery)

Topic 12

Development of a Proteomic Platform to Characterize Nanoparticles Corona Proteins

Prof.ssa Zampella Angela


CN3-Spoke 8 (Platform for DNA-RNA delivery)

Topic 13

Validating acid nucleic-based drugs using in vitro and in vivo models of cancer

Prof. Cirino Giuseppe

CN3-Spoke 9 (From target to therapy and competence center)

Topic 14

Maternal separation and cerebellum: a study of psychological and neuronal vulnerability to early life stress

Proff. Miniaci Maria Concetta-Perrone Capano Carla



Topic 15

Neuronal control of intestinal barrier function

Prof.ssa Aviello Gabriella



Topic 16

Design and synthesis of molecular hybrids between drugs for dermatological disorders or wound healing and H2S donors

Prof. Frecentese Francesco



Topic 17

Discovery of potent and selective Direct Antiviral Agents (DAA)

Proff. Summa Vincenzo-Guidotti Luca


DM217 (Ospedale San Raffaele)

Topic 18

Analysis, composition, exposure and risk assessment of atmospheric particulate matter and characteristic pollutants supporting public organizations

Proff. Perissutti Elisa-Magli Elisa


DM118 Pubblica Amministrazione

Topic 19

Molecular and cellular mechanisms linking air pollution and lung diseases

Prof.ssa Roviezzo Fiorita


DM118 Pubblica Amministrazione

 Topic 20

Computational approaches of Drug utilization applied to Health Big Data to support health policies for chronicity management

Proff. Menditto Enrica-Orlando Valentina


DM118 Pubblica Amministrazione

 Topic 21

Computational methods of Drug Utilization and Pharmacoeconomics for Healthcare policies in order to develop new regulatory processes for Advanced Therapies

Proff. Orlando Valentina-Menditto Enrica.


DM118 Pubblica Amministrazione

Topic 22

Mimetics of SOCS proteins as antinflammatory therapeutics in cancer

Proff. Marasco Daniela-Falcigno Lucia

Convenzione AIRC

Topic 23

Portable diagnostics for liquid biopsy application

Prof. Cinti Stefano

Convenzione AIRC

Topic 24

Elucidating the role of Neuregulin 1 on the neuroinflammatory and behavioral profile in the early-life immune activation mouse model of autism: focus on the brain-gut axis

Proff. Mattace Raso Giuseppina-De Simone Roberta


Convenzione ISS

Topic 25

Targeting arginase 2 to disrupt the immunosuppressive tumour microenvironment and promote gastric cancer response

Dott.ssa Sodano Federica


Convenzione AIRC

Topic 26

Preclinical development of Ru-based nanoformulation for cancer therapy

Proff. Irace Carlo-Santamaria Rita

Topic 27

New RNA-based therapeutic strategies to overcome chemoresistance in colorectal cancer

Proff. Russo Giulia-Russo Annapina

Topic 28

The role of phosphodiesterases in regulating the function of innate and adaptive immune cells in chronic respiratory diseases

Proff. Ianaro Angela-Tenore Giancarlo

Topic 29

TRPV3 in intestinal inflammation and colitis-associated cancer: functional role and pharmacological targeting

Proff. Pagano Ester-Izzo Angelo

Topic 30

Proposed Research Theme: IL-17A/IL-17RA axis in the association of autoimmune diseases with cardiovascular complications

Proff. Maione Francesco-Cirino Giuseppe

Topic 31

Metabolites from Cannabis – green expansion of chemical and biological space

Proff. Chianese Giuseppina-Taglialatela Orazio

 Topic 32

α-synuclein/hDAT interaction: a new target against Parkinson's Disease

Proff. De Simone Alfonso-Stornaiuolo Mariano

 Topic 33

Design and synthesis of nature-inspired compounds as potential anti-inflammatory/anticancer agents

Proff. De Marino Simona-D'Auria Valeria

Topic 34

Fragment-Based Ligand and Drug Discovery (FBLDD) via marine natural products to fight insulin resistance and inflammatory disorders associated with metabolic syndrome

Proff. Imperatore Concetta-Menna Marialuisa

Topic 35

Design, synthesis, physicochemical characterization, and biological evaluations of new drugs for inflammatory-based disease treatmen

Proff. Rimoli Maria Grazia- Albrizio Stefania

Topic 36

Antimicrobial peptides as promising agents able to counteract the antibiotic resistance of bacteria and protozoa

Proff. Grieco Paolo-Isabel Gomez Monterrey

Topic 37

Holistically sustainable multi-modal β-amyloid imaging

Proff. Brindisi Margherita-Summa Vincenza

Topic 38

Development of Ligands targeting Adenosine receptor A2A

Proff. Brancaccio Diego-Carotenuto Alfonso

Topic 39

Development of supramolecular peptide nanosystems for the delivery of new bioinorganic drugs

Proff. Tesauro Diego-Morelli Giancarlo

Topic 40

Multimeric G-quadruplex–forming DNA sequences: from characterization to the development of specific binders

Proff. Pagano Bruno-Giustiniano Mariateresa

Topic 41

Emerging toxins in italian seas and risks for human health

Proff. Dell'Aversano Carmela- Varra Michela